A natural product-like inhibitor of NEDD8-activating enzyme.
نویسندگان
چکیده
The natural product-like 6,6″-biapigenin has been identified as only the second inhibitor of NEDD8-activating enzyme using virtual screening. This compound was active in enzyme and cell-based assays, with potency in the micromolar range.
منابع مشابه
A Metal-Based Inhibitor of NEDD8-Activating Enzyme
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ورودعنوان ژورنال:
- Chemical communications
دوره 47 9 شماره
صفحات -
تاریخ انتشار 2011